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PiCTure - Prostate Cancer Treatment: the effect on health-related quality-of-life and other patient-reported outcomes
Status:
Cancer(s):
Research theme(s):
Research workstream(s):
Related staff:
Collaborators & co-investigators:
Dr Anna Gavin, Northern Ireland Cancer Registry
Dr Heather Kinnear, Northern Ireland Cancer Registry
Funding source:
Health Research Board
Prostate Cancer Charity UK
The PiCTure study is addressing the important question of the effect on men’s health-related quality-of-life of PSA testing, prostate biopsy and prostate cancer diagnosis, treatment and follow-up. Prostate cancer is the most commonly diagnosed cancer in men in Ireland. Incidence rates have been rising faster than those for any other cancer, largely as a result of widespread PSA testing.
A major concern of PSA testing is that it results in substantial over-diagnosis of prostate cancer and, consequently, over-treatment. In addition, most prostate cancer treatments are associated with significant risk of side-effects.
The PiCTure study has recruited more than 3,500 prostate cancer survivors from Northern Ireland and the Republic of Ireland. Data has been collected on a range of patient-reported outcomes including:
- treatment after-effects (such as impotence, incontinence and fatigue)
- health-related quality-of-life
- functional status
- psychological wellbeing utility (to inform assessment of cost-effectiveness of PSA testing
- and out-of-pocket expenses.
The study team are now collecting data from men undergoing prostatic biopsy in various centres across Ireland to assess whether this impacts on men’s health-related quality-of-life and psychological wellbeing.
Better understanding of the impact of prostate cancer on men’s lives may lead to the development of services to better support men.
- Mode of prostate cancer detection is associated with the psychological wellbeing of survivors: results from the PiCTure study
- Cancer-related symptoms predict psychological wellbeing among prostate cancer survivors: results from the PiCTure study
- Psychometric evaluation of the EORTC QLQ-PR25 questionnaire in assessing health-related quality of life in prostate cancer survivors: a curate's egg
- Lottery ticket was more effective than a prize draw in increasing questionnaire response among cancer survivors
- Patient reported "ever had" and "current" long term physical symptoms following prostate cancer treatments
- Long-term health-related quality of life of prostate cancer survivors varies by primary treatment. Results from the PiCTure (Prostate Cancer Treatment, your experience) study
- Prostate specific antigen testing is associated with men's psychological and physical health and their healthcare utilisation in a nationally representative sample: a cross-sectional study
- Factors predicting hospital length-of-stay after radical prostatectomy: a population-based study
- An all-Ireland population-based study of immediate and current physical and psychological side-effects of prostate cancer treatments
- An all-Ireland population-based study of past and current physical and psychological side-effects following prostate cancer treatments
- Associations between method of detection, clinical and socio-demographic factors and psychological well-being among prostate cancer survivors
- Actual and predicted treatment-related side-effects predict low health related quality-of-life in prostate cancer survivors PiCTure study
- Prostate cancer survivors who were symptomatic at diagnosis have an increased risk of poor psychological wellbeing than men who were asymptomatic. Results from an all-Ireland survey
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